摘要
目的 评价ＩＦＡＴ在湖南省疟疾监测中的应用效果。方法 选择桂东等３５个县（市）为调查点，新化等５县（市）为纵向监测点。以食蟹猴疟原虫作抗原，１：２０稀释样本血，用ＩＦＡＴ对疟疾的免疫诊断、血清流行病学调查和监测进行了观察。结果 间日疟抗体阳性符合率９９．０８％，ＧＭＲＴ ６２．３４，假阳性率０．８２％。佳东等３５个县（市）疟疾年发病率降至０．１‰以下４－１８年以后，ＩＦＡＴ平均阳性率１．６５％（６７０／４０６７６），新化等５县（市）纵向监测点平均阳性率２．１１％（５１１／２４２１１），结论 ＩＦＡＴ在间日疟诊断、血清流行病学监测中的敏感性、特异性高；同时表明全省疟疾防治效果巩固。
Objective To evaluate the effect of IFAT in malaria surveillance in Hunan Province. Methods Thirty - five counties( cities) were chosen for carrying out investigation and another 5 counties were chosen for performing longitudinal surveillance. IFAT was carried out for making observation on immunodiagnosis, seroepidemiological investigation and surveillance of malaria using plasmodium cynomolgi as antigen diluted at 1: 20. Results The positive coincidence rate for antibody against plasmodium vivax was 99.08% and GMRT was 62.34 and a false positive rate was 0. 82%. TFAT mean positive rate was 1.65% (670/40676) in the 35 counties (cities) investigated 4 - 18 years after malaria incidence dropped to lower than 0. 1 % and the mean positive rate in the 5 counties for longitudinal surveillance was 2. 11% (511/24211). Conclusion The sensitivity and specificity of IFAT were good in diagnosis and seroepidemtological surveillance of vivax malaria. It shows that the result of malaria control in this province is solid.
出处
《中国热带医学》
CAS
2001年第2期155-157,共3页
China Tropical Medicine
