摘要
目的探讨乳腺良性、交界性和恶性叶状肿瘤的外科治疗术式和预后因素。方法用Logistic回归和Cox模型单因素和多因素分析法对 2 0 3例乳腺叶状肿瘤的随访结果行统计分析。结果局部复发和因瘤死亡与组织学等级、局部复发与肿瘤的浸润性生长、因瘤死亡与核分裂和肿瘤性坏死有线性关系。核分裂和肿瘤性坏死是独立的风险因素。良性叶状肿瘤术后局部复发率为2 1 1% ,交界性为 4 5 2 % ,恶性为 6 4 3%。 5年生存率良性叶状肿瘤为 10 0 % ,交界性为 92 0 % ,恶性为 33 3%。结论对叶状肿瘤不宜采用肿物单纯切除术 ,良性和交界性应行区段切除术 。
ObjectiveTo study the treatment and prognosis of the breast phyllodes tumors.MethodsKG1Clinical data, and the results of follow-up in 203 cases of breast phyllodes tumors were analyzed using Logistic analysis and Cox regression in SPSS statistic software.ResultWT5”BZLocal recurrence and tumor mortality were in direct proportion to the pathologic grade of the tumor. There was a direct proportion between local recurrence and tumor infiltration; and between tumor caused-mortality and tumor mitosis and necrosis.Mitotic activity and tumor necrosis were the independent prognostic factors. After surgical resection 21 1% of patients with benign tumor, 45 2% of patients with borderline tumor, 64 3% of patients with malignant tumor suffered recurrence. The 5-year survival rate was 100% in patients with benign phyllodes tumor, 92 0% with borderline tumor, and 33 3% with malignance.KG2Conclusion Local excision is not the appropriate treatment for phyllodes tumor. Patients with benign or borderline phyllodes tumor should undergo wide local excision including a margin of uninvolved tissue, and that with local recurrent borderline and malignant phyllodes tumor receive mastectomy.
出处
《中华普通外科杂志》
CSCD
北大核心
2003年第10期612-615,共4页
Chinese Journal of General Surgery
关键词
乳腺叶状肿瘤
预后
外科治疗
术式选择
Breast neoplasms
Surgical procedures,operative
PrognosisHJHK
