摘要
目的 观察上呼吸道感染 (下称上感 )高热患儿短期使用肾上腺皮质激素 (下称激素 )对细胞免疫功能的影响。方法 在动物实验基础上 ,对 30例上感高热患儿应用病毒唑或抗生素 ,同时静滴地塞米松 0 .2～0 .4 mg/ kg,每日 1次 ,连用 3天。 3天后检测血中淋巴细胞亚群 ,随访 7天。结果 30例患儿体温均恢复正常 ,外周血 T淋巴细胞亚群均在正常范围 ,随访 7天未复发 ,亦无其他并发症。结论 上感高热患儿短期使用激素 ,可使体温稳步下降 。
Objective To observe the influence of children suffer with upper respiratory infection(URI)and high fever treated with short term cortin to cellular immunity.Methods 30 cases with URI and high fever was given dexamethasone 0.2~0.4mg/(kg·d) intravenously for 3 days and ribavirin or antibiotic was used at same time.Lymphocyte subsets were examed at 3th day and the patients were followed for 7 days.Results Fever was controlled in all 30 cases.Lymphocyte subsets were all within normal range after 3 days treatment.No relapse of URI and no any complication in the 30 cases were found within 7 days.Conclusions Short term cortin treatment may be used for upper respiratory infection with high fever.It has good effect on the decrease of fever and it has no influence to cellular immune function.
出处
《山东医药》
CAS
北大核心
2003年第25期8-9,共2页
Shandong Medical Journal
基金
山东省科委课题 (No.1999BBIDBAI
