摘要
为筛选盐酸环丙沙星片最佳处方和制备工艺，用正交试验法，考察低取代羟丙基纤维素的用量和制片压力对盐酸环丙沙星片的质量影响。制备的盐酸环丙沙星片各项指标符合规定，１５ｍｉｎ溶出度＞８０％。本法处方合理、工艺简单。
In
order to obtain the optimum prescription and preparing techniques of ciprofloxacin hydrocloride
tablets, the effects of the amount of L HPC,and the compaction pressure on the quality of
ciprofloxacin hydrocloride tablets were studied with orthogonal test. The result showed that the
ciprofloxacin hydrocloride tablets prepared could meet all the requirements, with the disolution of
>80% at 15 min.
出处
《广东药学院学报》
CAS
1999年第1期15-17,共3页
Academic Journal of Guangdong College of Pharmacy
关键词
盐酸环丙沙星片
正交试验法
制备工艺
溶出度
ciprofloxacin hydrocloride tablets
orthogonal experiment
design
preparing techniques
dissolution
