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3种预防顺铂所致呕吐方案的成本-效果分析 被引量:2

Cost-effectiveness Analysis of Three Preventing Schemes for Cisplatin-induced Vomiting
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摘要 目的:探讨不同药物治疗方案对同一疾病所产生的经济效果。方法:202例顺铂化疗患者,随机分为3组,分别给予舒必利、恩丹西酮和甲氧氯普胺进行预防呕吐治疗,运用药物经济学的成本-效果分析方法进行评价。结果:3种治疗方案中,舒必利方案有效率为87.1%,1个疗程费用为93.30元,有效率每增加1个百分点,成本为1.07元;恩丹西酮方案有效率为93.5%,1个疗程费用为448.26元,有效率每增加1个百分点,成本为4.79元;甲氧氯普胺方案有效率为57.5%,1个疗程费用为54.33元,有效率每增加1个百分点,成本为0.94元。结论:舒必利方案是3种治疗方案中较为合理的方案。 OBJECTIVE: To discuss the economic effects of different therapeutic schemes in the treatment of the same illness. METHODS: 202 cases receiving cisplatin chemotherapy were randomly divided into three groups according to the preventing schemes received:group I , sulpiride;group II ,ondansetron;group III, metoclopramide. Data was evaluated using phar-macoeconomic cost-effectiveness analysis. RESULTS: The effective rate of sulpiride was 87. 1%, expense of one therapeutic course being 93.30 yuans and increase of 1% effective rate costed 1.07 yuans.The effective rate of ondansetron was 93.5%, expense of one therapeutic course being 448. 26 yuans and increase of 1% effective rate costed 4. 79 yuans. The effective rate of metoclopramide was 57. 5%, expense of one therapeutic course being 54. 33 yuans and increase of 1% effective rate costed 0. 94 yuans. CONCLUSION :The sulpiride scheme is the most rational one.
作者 郑惠华
出处 《中国医院用药评价与分析》 2001年第5期284-285,共2页 Evaluation and Analysis of Drug-use in Hospitals of China
关键词 预防 顺铂 呕吐 成本-效果分析 舒必利 恩丹西酮 甲氧氯普胺 抗癌药物 cost-effectiveness analysis cisplatin-induced vomiting sulpiride ondansetron metoclopramide
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