摘要
目的 探讨五种小儿常见疾病的甲皱微循环变化。方法 应用甲皱显微镜对 98例五种小儿常见疾病患儿的甲皱微循环变化进行观察 ,并与 70例正常儿童比较。结果 :①五种疾病甲皱微循环的各项积分值和总积分值均明显增高。血液病、肾综、急性肾炎、肺炎组与健康儿组比较差异显著 (P <0 .0 5～ 0 .0 0 1)。癫痫组与健康儿组比较 ,无显著性差异 (P >0 .0 5 )。②血液病组甲皱微循环的总积分值明显高于其余 4组 ,与小儿癫痫、肺炎、肾炎组比较差异显著 (P <0 .0 5～ 0 .0 1)。与肾综组比较无显著性差异 (P >0 .0 5 )。③五种疾病治疗后甲皱微循环各项积分值及总积分值较治疗前明显下降。血液病、急性肾炎、肾综 ,肺炎组治疗前后比较差异非常显著 (P <0 .0 1～ 0 .0 0 1)。癫痫组治疗前后比较无显著性差异 (P >0 .0 5 )。结论 五种小儿常见疾病存在不同程度的微循环障碍 ,且随病情进展 ,变化显著。血液病患儿微循环障碍明显。加用 6 5 4-2及活血化瘀中药治疗后 ,甲皱微循环障碍明显改善。提示开展甲皱微循环检查不仅有助于小儿常见疾病病情的判断与疾病预后的估计 。
Objective: To investigate the changes of microcirculation in nail fold of patients with five common diseases in children. Methods: Microcirculation in nail fold in 98 children of five common diseases were measured by Microscope with nail fold,compared with that of 70 healthy children. Results: ① The every value integral and total value integral of microcirculation in nail fold of patient with blood disease,nephrotic syndrome,Acute glomerulonephritis,pneumonia were very significantly higher than that in the control group(P<0.05～0.001)?There was no significantly differences between Epilepsy group and control group(P>0.05).② The total value integral of microcirculation in nail fold of patient with blood disease were very significantly higher than that in the Epilepsy,Pneumonia,Acute glomerulonephritis(P<0.05～0.01)?There was no significantly difference between blood disease group and nephrotic syndrome group(P>0.05). ③ The every value integral and total value integral of microcirculation in nail fold in after therapy with blood disease,Nephrotic syndrome,Acute glomerulonephritis,Pneumonia were significantly lower than that in before therapy(P>0.01～0.001),but there was no significantly difference between after and therapy with Epilepsy group(P>0.05).Conclusions: Disturbed microcirculation are different degree in children of five common disease and there are correlated with disease severity.The disturbed microcirculation in children of blood disease significantly higher than that in another four group.The microcirculation in nail fold of patients in children were significantly improved by using 654-2 and traditional Chinese medicine for invigorating the circulation and resoluing the blood stairs.We considered that to carry out the examination of microcirculation in nail fold was not only beneficial to judge the patients condition and to evaluate the prognosis of the disease,but also useful to guide the treatment of common disease in children.
出处
《海南医学》
CAS
2001年第10期14-15,共2页
Hainan Medical Journal
