摘要
目的 评价注射用阿奇霉素治疗呼吸道感染的疗效与安全性。方法 随机将 10 4例呼吸道感染患者 ,分为两组 (每组 5 2例 )。治疗组用阿奇霉素 5 0 0 mg,静脉滴 ,每日一次 ,5～ 7日为 1个疗程。对照组用乳糖酸红霉素5 0 0 mg加入 5 %葡萄糖注射液 5 0 0 ml,静滴 ,每日 2次 ,5～ 7日为 1个疗程。结果 治疗组痊愈率 6 1.5 %、有效率96 .1%及细菌清除率 90 .3% ,均显著高于对照组 (2 8.8% ,75 .0 % ,75 .0 % )。试验组不良反应率 15 .3% ,显著低于对照组 (32 .6 % )。
Objective To evaluate the efficacy and safety of Azithromycin in the treathment of respiratory infections.Methods 104 patients with respiratory tract infection were divided into 2 groups (52 for each group). The treated group were given Azithromycin 500mg in 5% glucose injection 500ml, iv drip, qd, for 5～7 day.Results The treated group yielded a recovery rate 61.5%,the effective rate of 96.1% and the bacterial clearance rate of 90.3%, which were higher than the control group (28.8%, 75.0%, and 75.0%, respectively: p<0.01).Conclusion Azithromycin is an effective agent in the treatment of the acquired respiratory tract infection with slight adverse reaction.
出处
《临床肺科杂志》
2003年第6期511-512,共2页
Journal of Clinical Pulmonary Medicine
关键词
阿奇霉素
细菌感染
Azithromycin Bacterial infection
