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胰岛素样生长因子Ⅱ mRNA分析在肝癌诊断中的价值 被引量:5

Amplification of peripheral blood insulin-like growth factor II-mRNA and its clinical significance in the diagnosis of hepato-cellular carcinoma.
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摘要 甲胎蛋白(AFP)对肝癌(HCC)的诊断存在着较高的假阳性和假阴性.
出处 《中华肝脏病杂志》 CAS CSCD 2003年第11期695-696,共2页 Chinese Journal of Hepatology
关键词 胰岛素样生长因子Ⅱ MRNA 肝癌 诊断 基因扩增 Carcinoma, hepatocellular Insulin-like growth factor II Gene amplification Diagnosis
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参考文献6

  • 1Tetesuro S, Kankatsu Y, Kaoru S, et al. Increased expression of insulin-like growth factor 11 in hepatocellular carcinoma is primarily regulated at the transcriptional level. Lab Invest, 1996, 75:307-311.
  • 2Simms D, Cizdziel PE, Chomczyski P. TRIzol^TM: a new reagent for optimal single-step isolation of RNA. Focus, 1993, 15: 99-102.
  • 3Seo JH, Park BC. Expression of insulin-like growth factor II in chronic hepatitis B, liver cirrhosis, and hapatocellullar carcinoma.Gan Kagaku Ryoho, 1995, 22:292-307.
  • 4Edward T. Tumor suppressor genes, growth factor genes, and oncogenes in hepatitis B virus -associated hepatocellular carcinoma.J Med Virol, 1994, 42: 357-376.
  • 5Yao DF, Huang ZW, Chen SZ, et al. Diagnosis of hepatocellular carcinoma by quantitative detection of hepatoma-specific bands of serum gamma-glutamyl transferase. Am J Clin Pathol, 1998, 110:743-749.
  • 6Yao DF, Jiang DR, Huang ZW, et al. Abnormal expression of hepatoma specific gamma-glutamyl transferase and alteration of gamma-glutamyl transferase gene methylation status in patients with hepatocellular carcinoma. Cancer, 2000, 88: 761-769.

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