摘要
目的 评价内镜下注射止血和应用奥曲肽序贯治疗Dieulafoy病变的疗效。 方法 在内镜诊断为Dieulafoy病变所致出血后 ,先以高渗盐水 肾上腺素 (HSE)液注射止血 ,再连续应用奥曲肽 7d(0 .1mg ,皮下注射 ,1次 / 6～ 8h) ;未用奥曲肽或仅用 1～ 2d者为对照组。 结果 治疗组的再出血率和转手术率 (12 .5 % ,6 .3% )均显著低于对照组 (5 3.8% ,4 6 .2 % ;P <0 .0 5 )。结论 内镜下注射止血和应用奥曲肽的序贯疗法可明显减低Dieulafoy病变的再出血率和转手术率。
Objective To evaluate the efficacy of endoscopic injection hemostasis and sequential application of sandostatin in treatment of Dieulafoy's lesion. Methods After diagnosis of Dieulafoy's lesion confirmed, endoscopic injection hemostasis(EIH) together with mixture hypertonic saline and epinephrine(HSE) was performed, and then sandostatin was given consecutively for 7 days. The control group included the patients who were not given sandostatin or given just for 1 to 2 days. Results The rates of recurrent bleeding and transfer into surgery in sandostatin group were significantly lower than those in control group,(12.5% and 6.3% versus 53.8% and 46.2% respectively, P <0.05). Conclusion Endoscopic injection hemostasis combined with sequential application of sandostatin could obviously decrease the rates of recurrent bleeding and transfer into surgery of Dieulafoy's lesion.
出处
《中华消化杂志》
CAS
CSCD
北大核心
2003年第10期614-615,共2页
Chinese Journal of Digestion
