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抗枯宁的致突变性和致畸性研究

STUDIES ON THE MUTAGENIC!TY AND TERATOGENICITY OF KANGKUNING
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摘要 本文报道抗枯宁的致突变性和致畸性实验结果。结果表明,抗枯宁在Ames试验中,加和不加S_(99)A_(98)和A_(100)菌株回变菌落数均未超过自然回变菌落数的2倍,小鼠骨髓嗜多染红细胞微核试验和精子畸形试验结果阴性;抗枯宁没有致畸胎作用。 This paper reported the results of mutagenicite and teratogenicitic tests of Kangkuning. They showed that Kangkuning did not induce positive mutations of strains (TA_(98) and TA_(100)) with or without S_9 mix in the Ames test; there was no increase of micronucleus rate of polychromatic erythrocytes in mouse marrow; It did not increase morphological abnormality rate of sperm in mice; Kangkuning did not have teratogenises.
出处 《山西医学院学报》 1992年第3期216-219,302,共4页
关键词 抗枯宁 诱变性试验 致畸胎作用 Kankuning mutagenicity teratagenicity
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