摘要
目的 分析研究糖尿病合并菌阳肺结核的发病趋势,病变特点,疗效及转归。方法 对519例肺结核病人合并糖尿病51例中(9.8％)的菌阳肺结核32例进行临床分析。结果 显示糖尿病合并肺结核的例数,呈明显上升趋势,糖尿病合并菌阳肺结核比例明显高于菌阴肺结核,且糖尿病合并菌阳肺结核发病年龄,并发空洞的机会,复治比例,多耐药及持续菌阳比例均明显高于单纯菌阳肺结核。本组痰菌阴转时间平均为2.93月,较单纯菌阳肺结核痰菌阴转时间平均1.8月,明显延迟(p<0.01)。结论对于糖尿病合并菌阳肺结核病例,必须从一开始即采用强杀菌力的正规化疗方案,并确保足够疗程,根据耐药情况及时调整化疗方案,同时积极治疗控制糖尿病,才能获得满意疗效。
OBJECTIVE Analyzing the pathogenic trend, lesion characters, effectiveness of the treatments and the prognosis of sputum positive pulmonary TB with diabetes. METHOD The sample for analysis of 32 cases of sputum positive pulmonary TB with diabetes was taken from the 51 cases of pulmonary TB patients with diabetes that took 9. 8% of the 519 cases of registered TB patients. RESULTS The percentage of TB cases with diabetes showed significant rising. The eases of sputum positive pulmonary TB with diabetes were higher than that of sputum negative cases. The mean age of the occurrence of the sputum positive pulomnary TB eases with diabetes was much higher than simple sputum positive eases. Sputum positive TB cases with diabetes showed more chance of posilive sputum, complained cavities, easy recurrence, MTR and persistence posilive sputum than that of singular sputum positive cases. The mean time for the sputum of the sample group to turn negative was 2. 93 months much longer than that of simple sputum positive cases. CONCLUSIONS Regular regimen including powerful bactericides should be adopted for sputum positive TB with diabetes. The duration of the treatment should be long enough. The regimen should be adjusted according to the drug resistance spectrum and ,at the same time,diabetes should also be treated actively to get satisfactory treatment result.
出处
《中国初级卫生保健》
2003年第10期65-66,共2页
Chinese Primary Health Care
