摘要
目的 :探讨鼻窦癌累及眶内容的患者彻底切除病变并行眶内容整复手术的疗效。方法 :随机将晚期鼻窦癌 4 8例分成眶内容整复组和眶内容摘除组 ,比较 2组的手术方法 ,术后修复重建的效果 ,生存率以及生活质量。结果 :眶内容整复组 1、3、5年生存率分别为 73.0 5 %、6 4.4 6 %、32 .2 2 %。眶内容摘除组 1、3、5年生存率分别为 77.2 5 %、6 5 .37%、32 .6 8%。 5年生存率两组差异无显著性 (P >0 .0 5 ) ;眶周复发率分别为11%和 9% (P >0 .0 5 ) ;生活质量调查显示 ,眶内容整复组患者在躯体、心理、社会功能及物质生活方面均好于眶内容摘除组 (P <0 .0 5 )。结论 :对晚期鼻窦癌患者行眶内容整复术不降低其生存率 ;且基本保留了面容的完整性 ,保存了患侧视力 。
Objective:To explore the curative effect of orbit reconstruction for the patients with sinus carcinoma invading orbit.Methods:48 cases with sinus carcinoma of advanced stage were divided into two groups randomly .One was orbit reconstruction group,the other was orbit evisceration group.The surgery ,reconstruction,survival rate and quality of life were investigated. Results:For 1,3,5 year survival rate, orbit reconstruction group was 73.05%,64.46%, 32.22 %, and orbit evisceration group was 77.25%,65.37%,32.68%, there was no significant diffence of 5-year survival rate between two groups(P>0.05).The orbit recurrence rate was 11% and 9%, there was also no significant diffence between two groups(P>0.05). Quality-of-life questionnaire showed that orbit reconstruction group was better than that of orbit evisceration group at the aspects of body,psychology,social function and substance life(P<0.05). Conclusions:For the patients with sinus cancer of advanced stage, orbit reconstruction does not decrease the survival rate, but retain the face integrality, keep the vision and improve the quality of life.
出处
《山东大学基础医学院学报》
2003年第5期279-281,共3页
Journal of Preclinical Medicine College of Shandong Medical University
