摘要
分析了110例轻链(本周氏蛋白)尿的检测结果,阳性率热凝溶法为42.7%,蛋白电泳法为95.3%,抗轻链免疫法为100%。107例多发性骨髓瘤(MM)轻链尿的出现率为63.6%,呈游离型;其中单轻链尿占95.6%;IgD型、轻链病和多克隆型(IgG-IgA型和IgG-IgM型)轻链尿的出现率明显高于IgG和IgA型。36例肾脏病轻链尿的出现率为72.2%,呈结合型;其中双轻链尿占76.9%;以肾病综合征的出现率为最高,再则为慢性肾炎、尿毒症及肾盂肾炎。16例多克隆免疫球蛋白增殖病中SLE11例均为阳性,8例呈双轻链型(72.7%)。尿内3种免疫球蛋白均值,肾病综合征为380mg/L,SLE为204mg/L,慢性肾炎为186mg/L,明显高于多发性骨髓瘤的24.7mg/L。
One hundred and ten cases of light chain urine(LCU)were determined.The results were 1,42.7% of positive rate of LCU by heat-coagulate-dissolve method;2,95.3% of positive rate of LCU by urine ele-ctrophoresis method;3,100% of positive rate of LCU by anti-light-chain immune method.In one hundred and seven cases with multipe myeloma,the appearance rate of LCU was 63.6%.From among Mono-LCU was 95.6%.The appearance rate of IgD and polychonal type and light chain disease was higher than IgG and IgA type.In thirty-six cases with ranal disease,the ap-pearance rate of LCU was nephrotic syndrome>chronic nephritis>uremia>py-elonephritis.From among appearance rate of double-light-chain was 76.9%.In eleven cases with systemic lupus erythematosus,the appearance rate of LCU was 100$.From among double-LCU was 72.7%.In LCU of nephrotic syndrome(380mg/L)and SLE(204mg/L),the average of urine immunoglobulins was higher than of multiple myeloma(24.7mg/L).
出处
《山东医科大学学报》
1992年第3期231-234,共4页
Acta Academiae Medicinae Shandong
关键词
本周氏蛋白
轻链
红斑狼疮
尿
Bence-Jones protein
Immunoglobulins,Light chain
Multiple myeloma
Systemic lupus erythematosus
Nephrotic syndrome
Urine
Diagnosis,differential
