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早中期妊娠超声测量胎儿颈皮肤皱褶厚度的临床意义 被引量:3

Measuring the Thickness of Flexion Crease of Skin of Neck of Fetus in Early and Midtrimester Pregnant Women with Ultrasound
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摘要 目的 建立超声测量早、中期胎儿颈皮肤皱褶厚度 (NuchalSkinfoldThickness,NT)的正常参考值 ,为进行产前诊断胎儿染色体结构异常和基因结构异常提供参考。方法 经腹部超声 ,部分经阴道超声 ,对孕 10~ 2 6周 772例胎儿进行颈皮肤皱褶厚度测量 ,其中正常胎儿 75 1例 ,先天畸形儿、染色体结构异常、基因结构异常儿 2 1例。并对正常儿NT进行统计分析。结果 初步得出孕 10~ 2 6周正常胎儿NT的参考值范围。NT随孕周的增加而增长 ,两者呈高度正相关 (R =0 .92 6 ,P <0 .0 0 1) ,部分先天畸形胎儿如颈部水囊瘤 ,胎儿水肿等及染色体结构异常、基因结构异常儿NT增加。结论 孕 10~ 2 0周前NT随孕周增加明显 ,孕 10~ 2 0周是测量NT最佳时期。本文早、中期各孕周的NT参考值 ,对先天畸形胎儿的诊断及染色体结构异常、基因结构异常儿的筛查有重要参考价值。
出处 《中国现代医学杂志》 CAS CSCD 2003年第20期86-88,共3页 China Journal of Modern Medicine
基金 湖南省计生委科研课题 (编号 2 0 0 2 -0 9 2 0 0 2 -15 )
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参考文献10

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共引文献41

同被引文献9

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