摘要
目的 :评价呋塞米静脉滴注治疗难治性充血性心力衰竭 (CHF)的疗效。方法 :常规治疗加静脉注射呋塞米效果差的CHF 2 3例 ,继用呋塞米静脉滴注 5d ,观察其利尿效应 ,监测治疗前后血压、电解质、心率及体重。治疗过程中适当补充钠、钾和维持血压。结果 :静脉滴注呋塞米后每日尿量较治疗前明显增加 (P <0 .0 1) ;第 2、3、4、5天静脉滴注呋塞米量明显少于静脉滴注前 1天和静脉滴注第 1天剂量 (P <0 .0 5 <0 .0 1) ;治疗后心率、体重及血压显著降低 (P <0 .0 1,<0 .0 1,<0 .0 5 ) ,治疗前后血清钾和钠无明显改变 (均P >0 .0 5 )。治疗后所有患者临床症状和体征明显改善。结论 :在常规治疗下加用静脉滴注呋塞米治疗难治性CHF是一种安全有效的方法。
Objective:To evaluate the efficacy of furosemide intravenous infusion in refractory congestive heart failure (CHF). Methods:Twenty three CHF patients whose symptoms were refractory by bolus injection of furosemide and routinely therapeutic approach were treated with the intravenous infusion of high dose furosemide for 5 days, while blood pressure was maintained and proper KCl was administered daily. Heart rate, bodyweight, systolic and diastolic blood pressure, plasma electrolyte concentration were evaluated before and at the end of treatment. Results:Mean daily urinary volume was significantly higher after treatment with continuous infusion than that with bolus injection (P< 0.01 ); Heart rate, body weighy, plood pressure dreased significuntly after treatment (P< 0.05 ). The serum sadium and potassium did not differ significantly (P> 0.05 ). The sign and symptoms of all patients were ameliorated after treatment.Conclusion:It is a safe and effective method to treat refractory CHF patient with Furotemide intrevenous infusion.
出处
《临床心血管病杂志》
CAS
CSCD
北大核心
2003年第10期599-600,共2页
Journal of Clinical Cardiology
关键词
心力衰竭
充血性
呋塞米
Heart failure, congestive
Furosemide
