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降纤酶治疗急性脑梗死临床分析——附58例报告

Clinical Analysis of Treatment of Acute Cerebral Infarction with Defibrase:58 Cases Report
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摘要 目的 :探讨降纤酶治疗急性脑梗死的疗效。方法 :5 8例急性脑梗死患者随机分成 2组 ,治疗组 30例 ,对照组2 8例。两组均静滴 70 6代血浆 5 0 0ml、丹参 4 0ml,1次 d ,持续 1 5d。在此基础上治疗组静滴降纤酶第 1日 1 0Bu ,第3、5日各 5Bu ;两组患者治疗前后均做血液流变学、纤维蛋白原检查。结果 :治疗组血液粘度、血小板聚集率治疗前后有显著性差异 (P <0 .0 1 ) ,治疗后神经功能缺损检查积分减小、生活能力改善优于对照组 (P <0 .0 1 ) ,血浆纤维蛋白原与对照组相比差异有显著性 (P <0 .0 5 )。结论 Objective:To analyze the curative effect on cerebral infarction with defibrase.Methods: We fifty eight patients were randomly divided into treating group(TG,30 cases)and control group(CG,28 cases).TG was treated with defibrase intravenously 10 Bu on the first day,5 Bu on the third and fifth day each, while the control group was treated with 706 substitutive plasma 500 ml and Danshen 40 ml intravenously once a day lasting for 15 days.The two groups both were given blood dynamics and fibrinogen tests before and after the treatment.Results:The integral on defection of nervous function in TG groups was devreased after the defibrase treatment,and the life ability in TG group was much better than that in CG( P <0.01).Both blood viscosity and platelet coagulative rate had greatly changed after treatment( P <0.01).The plasma and fibrinogen in TG(193.63±89.13)were obviously different from that of CG (298.2±82.96).Conclusion:Defibrase is a safe and effective medicine to cure acute cerebral infarction.
机构地区 商洛市中医院
出处 《实用临床医学(江西)》 CAS 2003年第5期62-64,共3页 Practical Clinical Medicine
关键词 脑梗死 降纤酶 血浆纤维蛋白原 血液流变 cerebral defibrase plasma and fibrinogen blood dynarmics
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