摘要
目的:建立一种方便快捷的方法测定头孢噻肟钠原料粉中的残留溶媒乙酸乙酯及四氢呋喃的含量。方法:采用岛津 GC—17A 气相色谱仪,氮气为载体气体,以异丙醇为内标,程序升温进行测定。结果:该方法测定乙酸乙酯和四氢呋喃的精密度分别为(0.70%～1.87%)和(1.34%～1.91%)。方法回收率分别为100.2±2.7%和101.1±3.6%。结论:本方法适用于头孢噻肟钠的残留溶媒测定,方法简便快捷。
Objective:To build a GC—method for determining the concentration of trithy- lamine and tetrahydrofuran in cefotaxime raw powder.Method:the samples were determined by SHIMUZU GC—17A heated by computerized control with isopropyl alcohol as the internal stan- dard.Result:the assay precision of method to determine acetoactic ester and tetrahydrofuran were (0.70%～1.87%)and (1.34%～1.91%).the recovery rate of it were 100.2±2. 7% and 101.1± 3.6%.Conclusion:the method was convenient and fast for detecting the resdual in cefotaxime.
出处
《黑龙江医药》
CAS
2003年第5期426-427,共2页
Heilongjiang Medicine journal
