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BSS与LR对角膜内皮影响的评价 被引量:6

Clinical comparison of the effect of BSS and LR on corneal endothelium
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摘要 目的 评价白内障超声乳化手术中平衡盐溶液 (BSS)和乳酸钠林格液 (LR)对角膜内皮的影响。方法 白内障超声乳化手术 66例分为 2组 ,分别采用BSS和LR灌注液。用接触式角膜内皮镜和超声角膜测厚仪于术前、术后第 1天和 3月进行测量。结果 两组术后角膜内皮细胞密度和六角形细胞百分率降低 ,细胞面积变异系数和细胞平均面积增大。但BSS组的损伤程度小于LR组 (P <0 0 5 )。术后第 1天 ,两组的角膜厚度增加 ,BSS组厚度增加率小于LR组 (P <0 0 5 )。 3月后 ,角膜厚度恢复至术前水平。结论 BSS和LR液均对角膜内皮造成损伤。但BSS组影响小。两者在维持角膜脱水状态上无差异。对于经验丰富的术者 ,LR可以替代BSS。 Objective To evaluate the effect of BSS and LR on corneal endothelium during phacoemulsification.Methods In a prospective clinical study,senile cataract undergoing phacoemulsification were divided into two irrigating solution groups,BSS and LR.Contact specular microscopy and ulrtasonic pachymetry are used to detect the endothelial cell density,the coefficient of variation of cell area,the cell average area,the percentage of hexagonality and the corneal thickness preoperatively,at postoperatively 1 day and 3 month,respectively.Results In two groups,the morphologic changes of corneal endothelium are significant.But LR caused a more significant loss in the percentage of endothelial cell,coefficient of variation of cell area and the cell average area and a decrease in the cell density and the percentage of hexagonality.At 1 day after surgery,corneal thickness of both groups significantly increased and the percent change of thickness in LR group was more significant.After 3 months,the postoperative pachymeter was similar with the preoperative in two groups.Conclusion During phacoemulsification.both BSS and LR damaged the corneal endothelium and LR is more significant.On maintaining the dehydration of corneal endothelium,beteween the BSS and LR group have no differences.If the operator is skillful,we suggest LR be as the replacement of BSS.
出处 《眼外伤职业眼病杂志》 北大核心 2003年第8期533-535,共3页 Journal of Injuries and Occupational Diseases of the Eye with Ophthalmic Surgeries
关键词 白内障 超声乳化手术 平衡盐溶液 乳酸钠林格液 角膜内皮 Phacoemulsification Corneal endothelium Anterior chamber irrigating solution
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