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BiPAP呼吸机在慢性阻塞性肺疾病并Ⅱ型呼吸衰竭的早期应用 被引量:2

EARLY APPLICATION OF BiPAP VENTILATORS FOR PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE ACCOMPANIED BY TYPE Ⅱ RESPIRATORY FAILURE
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摘要 ①目的 探讨早期应用无创伤性口鼻面罩通气对慢性阻塞性肺疾病 (COPD)并Ⅱ型呼吸衰竭的治疗效果。②方法 在常规治疗基础上早期采用BiPAP呼吸机治疗COPD并Ⅱ型呼吸衰竭病人 30例 ,观察治疗前、治疗后 (疗程 7~ 10d)动脉血气分析的变化 ,并监测SaO2 、血压、脉搏的变化。③结果 COPD并Ⅱ型呼吸衰竭病人治疗后与治疗前比较 ,pH、PaO2 升高 ,PaCO2 降低 ,差异均有显著性 (t=2 .4 5 8~ 7.85 3,P <0 .0 5 ) ,且病人呼吸频率及心率减慢 ,气促症状减轻。④结论 早期应用BiPAP呼吸机治疗COPD并Ⅱ型呼吸衰竭疗效肯定 。 Objective To evaluate the treatment outcome of the early application of non-invasive mouth and nose mask ventilation in patients with chronic obstructive pulmonary disease(COPD) accompanying type Ⅱ respiratory failure. Methods BiPAP ventilators were applied at an early stage to treat 30 COPD patients with type Ⅱ respiratory failure on the basis of routine therapy. The changes of arterial blood gas, oxygen saturation, blood pressure, and heart rates were observed before and after the treatment. Results Compared with the results before the treatment, the levels of pH and PaO 2 of the 30 patients increased, and that of PaCO 2 decreased, both with significant differences (t=2.458-7.853, P<0.05). Breathing frequencies and heart rates decreased, with short breath improved. Conclusion An early application of BiPAP ventilators in COPD patients with type Ⅱ respiratory failure has a positive result, and can prevent the occurrence of severe respiratory failure.
作者 王美 秦筱梅
出处 《齐鲁医学杂志》 2003年第3期291-292,共2页 Medical Journal of Qilu
关键词 慢性阻塞性肺疾病 Ⅱ型呼吸衰竭 BIPAP呼吸机 治疗 呼吸功能不全 动脉血气分析 ventilators, mechanical pulmonary disease, chronic obstructive respiratory insufficiency
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  • 1Brochard,Mancebo J,Wysocki M,et al.Noninvasive ventilation for acute exacerbations of chronic obstructive pulmonary disease[J].N Engl.J Med,1995,333:817.
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  • 4Plant PK.Owen JL.Elliott MW.Early use of non invasive ventilation for acute exacerbations of chronic obstructive pulmonary disease on general respiratory Wardsia multicenter randomized controlled trial[J].Lancet,2000,355:1931.

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