摘要
目的 研究近年来北京地区非伤寒沙门氏菌肠炎患者的临床特征、流行病学特征及其耐药情况 ,为本地区的流行病学研究及临床合理用药提供依据。方法 用 SS琼脂及伊红美兰琼脂培养基培养阳性的沙门氏菌 ,采用血清凝集法鉴定分型 ,同时采用 K- B纸片法检测药物敏感性。结果 沙门氏菌肠炎主要是由肠炎血清型和鼠伤寒沙门氏菌血清型所引起 ,幼儿发病比率较高 ,与不洁饮食有一定关系。春、秋季为该病新的发病高峰。该病以发热、腹痛、腹泻为主要临床表现 ,76株非伤寒沙门氏菌药敏结果显示该菌对喹喏酮类药物耐药率较高。结论 非伤寒沙门氏菌肠炎是临床常见的腹泻性疾病 ,近年该菌在流行病学方面表现出新的特征 ,患者临床表现仍以发热、腹痛、腹泻为主 ,应加强其对喹喏酮类药物的耐药性监测。
Objective To study the clinical and epidemical characteristics of non-Salmonella typhi enteritidis patients and its antimicrobal resistance of Salmonella enteritidis in Beijing area recent years in order to provide the basis for local epidemical study and the rational clinical treatment. Methods The positive strains cultured by Salmonella-Shigella agar (SS), and Eosin Methylene Blue Agar medias were identified by serum agglutination method, and the antimicrobial resistance of Salmonella enteritidis was detected by NCCLS recommended K-B disc diffusion method. Result In the past few years, the majority serotypes including Salmonella enteritidis and Salmonella typhimurium, most of infants affected were due to insanitary living condition. The main clinical symptoms including fever, abdominal pain and diarrhoea. 76 strains of Salmonella enteritidis showed high resistance to quinolones. Conclusions non-Salmonella typhi enteritidis is a main cause of diarrhoeal disease. The constant monitoring of antimicrobal resistance of Salmonella enteritidis to quinolones is one of the important measures for the prevention of the epidemic spread of the disease.
出处
《中国抗生素杂志》
CAS
CSCD
北大核心
2003年第9期552-554,共3页
Chinese Journal of Antibiotics
关键词
肠炎沙门氏菌
临床
耐药
Salmonella enteritidis
Clinical characteristics
Drug resistance
