摘要
生物膜干涉技术可以实现生物分子之间相互作用的实时分析检测,广泛应用于高校科研实验室的药物开发过程,是一种非标记的、实时监测的先进技术。本文结合生物分子相互作用分析系统的技术原理和实际使用情况,详尽叙述了其在生物分子间相互作用检测的方法和应用,旨在为相关领域的科研工作者提供实验帮助和参考。
Octet biomolecule interaction analysis system is a multi-functional,label-free,real-time analysis instrument.It is ideal for rapidly measuring concentration of proteins and other biomolecules,measuring kinetics and affinity,and screening proteinprotein and protein-small molecule interactions.In this paper,based on the technical principle and practical application of biomolecular interaction analysis system,the method and application of biomolecular interaction detection system are described in detail,aiming at providing experimental help and reference for researchers in related fields.
作者
张艳
姜丽艳
张晓光
李帅
张爱军
高贵
ZHANG Yan;JIANG Liyan;Zhang Xiaoguang;LI Shuai;ZHAGN Aijun;GAO Gui(School of Life Sciences,Jilin University,Changchun 130012,ChinaCollege of Food Science and Engineering,Jilin University,Changchun 130012,China)
出处
《生命科学仪器》
2019年第2期49-52,42,共5页
Life Science Instruments
基金
"985"学科及实验室
平台基地建设项目
国家自然科学基金项目(31701713)
吉林省教育厅"十三五"科学技术项目(JJKH20180175KJ)
