摘要
目的 :观察静脉注射剂佩尔地平对高血压急症的疗效。方法 :选择 2 0例高血压急症住院患者使用静脉注射佩尔地平治疗 ,并记录 0 .5、1、2、4、6、12、18及 2 4h血压和心率。结果 :2 0例中除 1例因不能耐受的头痛而退出外 ,19例患者在 0 .5h内血压明显下降 :收缩压由 (2 0 8.2± 14 .7)降至 (2 0 1.8± 13.3)mmHg(1mmHg =0 .133kPa) ,t =5 .6 7,P <0 .0 1) ;舒张压由 (118.3± 6 .7)降至 (10 9.7± 5 .4 )mmHg (t =6 .2 1,P <0 .0 1) ,显效率为 95 % ,有 3例 (15 % )有心悸副作用。结论 :静脉注射佩尔地平降低血压疗效肯定 ,使用安全、简单 ,副作用轻微 。
Objective:To evaluate the efficacy and side effects of perdipine for hypertensive emergency. Methods: Twenty patients with hypertensive emergency received continuous intravenous infusion of perdipine. Results:The blood pressure decreased in 30 minutes after intravenous infusion, systolic blood pressure decreased from ( 208.2 ± 14.7 ) to ( 201.8 ± 13.3 )mm Hg (P< 0.01 ), diastolic blood pressure decreased from DBP ( 118.3 ± 6.7 )mm Hg to ( 109.7 ± 5.4 )mm Hg (P< 0.01 ). One patient was ruled out because of severe headache. Patients had slightly tachycardia. Conclusion:Continuous intravenous infusion of perdipine is an effective and safe therapy on hypertensive emergency.
出处
《临床心血管病杂志》
CAS
CSCD
北大核心
2003年第9期537-538,共2页
Journal of Clinical Cardiology
