摘要
目的:观察壳聚糖对肝癌实体瘤(Heps)小鼠的抑瘤作用和免疫调节作用。方法:建立荷肝癌小鼠模型,观察壳聚糖对肿瘤生长和自然杀伤细胞(NKC)、巨噬细胞(M)吞噬功能、T淋巴细胞转化功能的影响。结果:壳聚糖对小鼠Heps无明显抑制作用,低剂量壳聚糖可增加Heps荷瘤小鼠的细胞免疫功能,对M吞噬功能有明显的提高作用。结论:壳聚糖对荷瘤小鼠的免疫功能具有调节作用。
Objective:To observe and study cancer inhibition and immunity adjust effect of Chitosan on mouse with liver cancer by experiment. Methods:Set up the model of the mouse with liver cancer, observe the effect of Chitosan on cancer growth,the function of lick up of NK cell and M, and the diversion of T cell. Results:Chitosan has no effect of inhibition on Heps of mouse, low dose Chitosan can not only enhance the effect of immunity of the mouse with liver cancer, but also clearly augment the effect of lick up of the M.Conclusion:Chitosan can adjust the effect of immunity of the mouse with liver cancer.
出处
《中国药业》
CAS
2003年第9期26-27,共2页
China Pharmaceuticals
关键词
壳聚糖
押瘤作用
免疫调节
Chitosan
Cancer Inhibition
Immunity Adjust
