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肥大细胞与神经系统的相互作用 被引量:16

Interactions of mast cells with the nervous system
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摘要 肥大细胞是正常情况下存在于中枢神经系统内并和外周神经有密切关系的一类免疫反应细胞。肥大细胞在脑和脑膜内主要围绕血管周围分布,血管壁内和脑实质内为散在;肥大细胞和周围神经末梢在广泛部位有密切接触,有时呈胞膜对胞膜接触,但并不形成类似突触的关系。神经系统经典递质、肽类递质、嘌呤类递质、一氧化氮以及很多神经来源的细胞因子都对肥大细胞的数量及功能有调节作用;这些作用有些是对机体有益,有些则不利。肥大细胞对神经系统的生理作用可能包括参与摄食、体温、生殖、生殖内分泌活动及神经免疫内分泌调节。有趣的是有些研究认为肥大细胞不但参与I型变态反应,而且也有可能激活肾上腺皮质反应对抗I型变态反应。
出处 《中国临床康复》 CAS CSCD 2003年第22期3110-3112,共3页 Chinese Journal of Clinical Rehabilitation
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参考文献22

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二级参考文献21

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