摘要
研究了 3 ,5 二芳基 4,5 二氢异唑化合物 ( 1a～ 1e) ,1,4 二氢吡啶化合物 ( 3a～ 3c)和 1,3 ,5 三苯基 4,5 二氢吡唑化合物 ( 5 )分别在二铬酸氢四吡啶合镍 (II) [(Py) 4 Ni(HCrO4) 2 ]氧化下脱氢反应的结果 ;研究了在 [(Py) 4 Ni(HCrO4) 2 ]存在下 ,吡啶叶立德、喹啉叶立德或异喹啉叶立德分别和缺电子烯烃反应 ,一步法合成中氮茚衍生物 9a～ 9b ,11a～ 11b ,13的结果 .发现金属配合物氧化剂二铬酸氢四吡啶合镍 (II)可用于多类杂环化合物的脱氢芳构化 .
Aromatization of 3,5-diaryl-4,5-dihydroisoxazoles (1a～1e), 1,4-dihydropyridines (3a～3c) and 1,3,5-triphenyl-4,5-dihydropyrazole (5) were promoted by tetrakis-pyridine nickel(II) dichromate to yield the corresponding 3,5-diarylisoxazoles (2a～2e) in moderate yields (52%～72%), pyridine derivatives (4a～4b) in moderate to high yields (79%～88%) and 1,3,5-triphenylpyrazole (6) in 81% yield, respectively. A one-pot procedure was developed to prepare the derivatives of indolizines 9a～9b, 11a～11b and 13 in moderate to high yields (84%～93%) by the reaction of pyridinium N-ylides, isoquinolinium N-ylides or quinolinium N-ylides with electron-deficient 8a～8b in the presence of tetrakispyridine nickel(II) dichromate (TPND). The results showed that TPND possesses very good activities on the aromatization of N-containing heterocyclic compounds.
出处
《有机化学》
SCIE
CAS
CSCD
北大核心
2003年第8期794-798,共5页
Chinese Journal of Organic Chemistry
基金
国家自然科学基金 (No.2 0 0 72 0 1 6)
江苏省教育厅自然科学基金 (No.0 0KJD1 50 0D1 )
南京师范大学环境友好化学重点实验室资助项目
