摘要
目的 研究TumorM2 PK在健康人、炎症性消化系统疾病以及良、恶性消化系统肿瘤病人血浆中的平均水平 ,并加以比较 ,从而探讨TumorM 2 PK在消化系统肿瘤实验室诊断上的意义。方法 利用夹心ELISA法定量检测 1 5 9名上述人群EDTA 血浆中的TumorM2 PK的平均水平。结果 恶性消化系统肿瘤组TumorM2 PK分别与健康人、炎症性消化系统疾病以及良性肿瘤组之间的差异显著 (P <0 .0 0 1 ) ,特异性高达 90 .5 % ,健康人、炎症性消化系统疾病以及良性肿瘤组之间则没有显著性差异 (P >0 .0 5 )。结论 研究证明 ,TumorM2 PK在恶性消化系统肿瘤(胃癌、结肠癌、胰腺癌 )患者的血浆中均有明显升高 ,其检测结果具有临床诊断价值 ,而在炎症性消化系统疾病以及良性肿瘤时则维持在基本正常的水平 。
Objective To study and compare the level of Tumor M2 PK in the EDTA plasma of healthy controls, Inflammatory digestive system disease, Benign, Malignant digestive system tumors,and discuss the significance in diagnosis of digestive system tumors. Methods Tumor M2 PK of 159 above mentioned people can be quantified in EDTA plasma with a commercially available ELISA test kit. Result Tumor M2 PK level had a statistical difference while respectively comparing the malignant digestive system tumor with healthy controls, Inflammatory digestive system disease and benign tumors (P<0.001) ;There are not significant difference among the healthy controls, Inflammatory digestive system disease and benign tumors (P>0.05). Conclusion With this test we found the level of Tumor M2 PK in the EDTA plasma of malignant digestive system tumor(gastric cancer, colorectal cancer, pancreatic cancer ) is remarkable higher than others, This result indicates the value of M2 PK in clinical diagnosis However, it remains the normal level in healthy controls, Inflammatory digestive system disease and benign tumors , Therefore Tumor M2 PK could be an index for clinical diagnosis and screening of tumor patients.
出处
《辽宁医学杂志》
2003年第4期179-181,共3页
Medical Journal of Liaoning
