摘要
目的检测原发性高血压患者细胞间粘附分子 (ICAM 1 )水平并探讨其在原发性高血压发病中的意义。方法采用流式细胞测定法测定 45例原发性高血压患者和 1 5例健康体检者ICAM 1水平。结果原发性高血压Ⅰ期、Ⅱ期与Ⅲ期患者ICAM 1水平明显高于正常对照组 (P <0 .0 5) ,Ⅲ期患者ICAM 1水平显著高于Ⅰ期患者 (P <0 .0 5)。结论原发性高血压患者ICAM 1水平明显增高 ;血压控制时 ,ICAM 1水平仍高 ;Ⅲ期患者ICAM 1水平增高更为显著。
Objective To detect the level of intercellular adhesion molecule 1(ICAM 1) in the patients with essential hypertension and to study its significance. Methods ICAM 1 levels in 45 essential hypertension patients and 15 normal controls were detected by flow cytometry. Results ICAM 1 levels in the essential hypertension patients(I, II, and III stage) were significantly higher than that in the controls(P<0.05), and the ICAM 1 levels in the III stage patients were significantly higher than that in the I stage patients(P<0.05). Conclusion ICAM 1 level in the essential hypertension patients is obviously increased, which remains high when the blood pressure is controlled. ICAM level in the III stage patients is more significantly increased.
出处
《中国综合临床》
北大核心
2003年第9期776-777,共2页
Clinical Medicine of China
关键词
高血压
原发性
细胞间粘附分子
Hypertension,essential
Intercellular adhesion molecule
