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SARS病毒免疫学性状的结构基础分析 被引量：1

Analysis of Structure Basis of Immunology Characters of SARS Coronavirus
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摘要 运用生物信息学技术 ,对SARS冠状病毒基因组及其编码区进行了全序列分析 ,根据其基因和推导蛋白结构特点及同源性分析 ,探索SARS病毒主要结构蛋白免疫学性状的结构基础及进一步进行免疫学研究的线索 。 Using bioinformatic methods, the characters of SARS coronavirus genome and it's encoding region were analyzed and predicted. The preliminary speculation on structure basis of immunology character of structure proteins of SARS coronavirus was undertaken by means of sequence analysis. The result of T/B cell epitopes of SARS coronavirus spike protein implied that its immunogenic characteristics were unique in the coronaviruses family. These data can provide some information for the further study on the diagnosis and prevention of SARS virus. ;
作者 刘龙丁 董少忠 李建峰 李琦涵
机构地区 中国医学科学院中国协和医科大学医学生物学研究所
出处 《中国生物工程杂志》 CAS CSCD 2003年第5期6-11,共6页 China Biotechnology
关键词 SARS病毒 免疫学性状 结构 严重急性呼吸综合征 基因组 冠状病毒 SARS Coronavirus Immunology character Genome
分类号 R373.1 [医药卫生—病原生物学] R563.1 [医药卫生—呼吸系统]
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参考文献13

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同被引文献13

  • 1常静.针对SARS患者的特异性抗体检测结果不容乐观[J].中华医学信息导报,2003,18(13):4-5. 被引量：1
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中国生物工程杂志
2003年 第5期

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