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多发性硬化患者的听神经损害 被引量：3

Auditory nerve impairment in the patients with multiple sclerosis
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摘要 多发性硬化(multiplesclerosis,MS)是以中枢神经系统多灶炎症及脱鞘为特征的一种疾病。MS患者中存在听神经的损害的表现,有人观察到3.5%确诊的MS患者在急性期及复发期出现单侧或双侧听力下降。2%～10%MS患者出现脑干诱发电位(brainstemauditoryevokedpotential,BAEP)I波异常,表现为波I潜伏期延长、波幅降低甚至缺失。这些表现随病情的加重明显,随症状的减轻而减轻,甚至恢复正常。MRI显示MS患者听神经病灶,表明听神经周围部分的损害,其原因可能与听神经根的颅外部分出现脱髓鞘有关。
作者 曾丽 郑金瓯
机构地区 广西医科大学第一附属医院神经内科
出处 《中国临床康复》 CSCD 2003年第13期1948-1949,共2页 Chinese Journal of Clinical Rehabilitation
关键词 多发性硬化 听神经损害 脑干诱发电位 急性期 复发期 并发症
分类号 R744.51 [医药卫生—神经病学与精神病学]
  • 相关文献

参考文献12

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二级参考文献10

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共引文献7

同被引文献18

  • 1宋鹏,龚树生,罗凌惠,黄翔,程庆,曾祥丽.周围神经脱髓鞘豚鼠模型听神经病变及听功能研究[J].临床耳鼻咽喉科杂志,2005,19(10):461-465. 被引量：8
  • 2石力,王锦玲,邱建华,苏钰,刘顺利.PLP_(139-151)多肽诱导实验性自身免疫性脑脊髓炎大鼠的听觉和形态学改变[J].听力学及言语疾病杂志,2006,14(3):202-206. 被引量：2
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  • 7de Seze J, Assouad R, Stojkovic T, et al. Hearing loss in multiple sclerosis : clinical, electrophysiologic and radiological study [ J 1. Rev Neurol (Paris) , 2001,157 ( 11 Pt 1 ) : 1403 - 1409.
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  • 10Ito T, Tokariki M, Sbibamori Y, et al. Cochlear nerve demyelination causes prolongation of wave Ⅰ latency in ABR of the myelin deficient (md) rat[J]. Hear Res, 2004,191(1 -2) :119 -124.

引证文献3

二级引证文献8

中国临床康复
2003年 第13期

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