摘要
目的 探讨黄体酮对氢溴酸东莨菪碱 (SCOP)所致小鼠学习记忆损害的影响。方法 水迷宫法测定黄体酮对SCOP所致小鼠学习记忆损害的改善作用。结果 黄体酮 4mg·kg-1、8mg·kg-1体重可明显减少小鼠在水迷宫中的平均游出时间。
Objects To inspect progesterone's effects on learning and memory impairments induced by scopolamine hydrobromide (SCOP).Methods Morris water maze was used to measure the extent of improved mice's learning and memory impairment caused by SCOP with progesterone.Results The average time for mice swimming out of the Morris water maze was reduced after injection with progesterone 4-mg·kg -1 and 8-mg·kg -1 in mice.Conclusions Progesterone may improve learning and memory impairments caused by SCOP.
出处
《新乡医学院学报》
CAS
2003年第3期187-188,共2页
Journal of Xinxiang Medical University
关键词
黄体酮
水迷宫
氢溴酸东莨菪碱
学习记亿
progesterone
Morris water maze
scopolamine hydrobromide
learning and memory
