摘要
为进一步探讨Amplatzer动脉导管未闭堵塞器治疗动脉导管未闭(PDA)的方法及疗效 ,于1998年8月～2001年12月应用Amplatzer堵塞器治疗PDA患儿210例 ,年龄4.5±2.8岁(0.6～12岁) ,PDA平均最小直径3.89±1.32mm(1.6～6.9mm),堵塞器直径比PDA最小直径大2.5～6mm ,伴肺动脉高压者选用的堵塞器相对较大。在舒张期多次测量PDA直径 ,如左侧位主动脉造影不能清晰显示PDA ,加做右前斜位主动脉造影。堵塞术后行彩色多普勒随访。结果显示 ,所有PDA临床关闭(听诊无杂音) ,出院时达100 % ,超声彩色多普勒检查在出院时无分流达98.6 % ,堵塞术后3月达100% ;超声多普勒随访发现左肺动脉流速在1.5～1.7m/s间6例 ,都为小于1岁婴儿并伴有肺动脉高压 ,且堵塞器直径大于PDA直径3.5mm以上 ;未发生溶血、堵塞器脱落或堵塞器断裂、PDA再通、血栓栓塞、心内膜炎、主动脉狭窄等。提示AmplatzerPDA堵塞器可安全有效地应用于直径1.6mm以上的PDA 。
To explore the efficacy of transcatheter closure of patent ductus arteriosus(PDA)with Am-platzer duct occluder(ADO)and to discuss the factors that influence the results.Transcatheter closure of PDA with ADO was performed in210cases aged between6months and12years(median:4.5years).The narrow-est diameter of PDA was between1.6and6.9mm.Results:The device was successfully implanted in210patients.The clinical closure rate was100%at discharge,and the complete echo cardiograph closure rate was98.6%(207/210)and gradually increased to100%at3- month follow-up.Doppler ultrasound evaluation shown a Doppler velocity of>1.5m/s in6infants,all of them complicated pulmonary hypertension.There was no clinical evidence of hemolysis and no incidence of device embolization,aortic arch obstruction or bacterial arteritis,suggesting that Amplatzer duct occluder was a safe and effective technique for the catheter closure of PDA that over1.6mm.It was also important to avoid the iatrogenic obstruction of the left pulmonary artery.
出处
《临床儿科杂志》
CAS
CSCD
北大核心
2003年第5期267-269,共3页
Journal of Clinical Pediatrics
基金
上海第二医科大学自然科学研究基金项目 (编号 :2001校04)
