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荧光定量PCR检测HBV DNA 被引量:2

NUCLEIC ACID QUANTIFYING ASSAY OF HEPATITIS B VIRUS AND ITS CLINICAL SIGNIFICANCE
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摘要 目的 :探讨血清 HBV DNA水平与 HBV标志物 (HBV M)表现模式的关系。方法 :对 12 0 7例慢性乙型肝炎患者进行血清 HBV DNA荧光定量 PCR分析 ,HBV M检测采用 EL ISA法。结果 :血清 HBV DNA水平与 HBVM表现模式有关 ,HBs Ag与 HBe Ag的存在影响 HBV DNA水平变化。结论 :HBe Ag和 HBV DNA有明显的相关 ,抗 - HBe、抗 HBc阳性者病毒未完全停止复制 ,只是复制水平降低。 Objective:To explore the relation between the nucleic acid content of hepatitis B Virus and hepatitis B virus markers.Methods:1207 patients Suffering from Chronic hepatitis B were performed Amplisensor ration PCR analysis was used for HBV DNA quantifying assessment.Hepatitis B virus markers were detected by ELISA.Results:Serum HBV DNA content was related to hepaitis B virus markers.Conclusions:Thers is a Significant correlation between HBeAg and HBV DNA,but positive Anti-HBe and Anti-HBc have copies lower cover.
出处 《现代预防医学》 CAS 2003年第3期326-327,共2页 Modern Preventive Medicine
关键词 荧光定量PCR 检测 HBV DNA 慢性乙型肝炎 血清 Hepatitis B Virus HBVM HBVDNA Amplisensor
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  • 1闫涛,季伟,王慧芬,张爱民,李梵.乙型肝炎病毒感染后机体免疫反应的研究进展[J].国外医学(流行病学.传染病学分册),2004,31(4):219-222. 被引量:14
  • 2程良斌.香菇多糖的作用机理及临床应用[J].中西医结合肝病杂志,1997,7(1):59-62. 被引量:33
  • 3Honkoop P,Niesters HG,de Man RA,et al.Lamivudine resistance in immunocompetment chronic hepatitis B incidence and patterns[J].J Hepatol,1997,26(6):1393-1395.
  • 4Niesters HG,Honkoop P,Haagsma EB,et al.Identification of more than one mutation in the hepatitis B virus polymerase gene arising during prolonged lamivudine treatment[J].J Infect Dis,1998,177(5):1382-1385.
  • 5NOWARK M A,BONHOEFFER S,HILL A M,et al.Viral dynamics in hepatitis B virus infection[J].Proc Natl Acad Sci USA,1996,93(9):4398-4402.
  • 6YOFFE B,BURNS D K,BHATT H S,et al.Extrahepatic hepatitis B virus DNA sequences in patients with acute hepatitis B infection[J].Hepatology,1990,123(12):187-192.
  • 7KROGSGARRD K,MATHIESEN L R,ALDERSHVILE J,et al.Delta infection and hepatitis B virus in Danish patients with fulminant hepatitis B[J].Scand J Infec Dis,1988,20(2):127-133.
  • 8KOBARASHI H,SUZUKI T,KINOSHITA N,et al.Susceptibility of hepatitis B virus to disinfections of heat[J].J Clin Microbiol,1984,20(2):214-216.
  • 9BOND W W,HERITAGE I D,FCORES G H,et al.Inactivation of hepatitis B Virus by intermediate to high level didinfectant chemics[J].J Clin Microbiol,1983,18(3):535-538.
  • 10牟玲,王佳贺,王英,李忠训,王英烈.干扰素治疗慢性乙型肝炎疗效与HBV-DNA水平研究[J].中国医师杂志,2000,2(7):437-437. 被引量:1

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