摘要
目的 建立一种注射用头孢呋辛钠含量的测定方法。方法 以水为溶剂 ,采用旋光法测定。结果 在 2～ 1 0mg·ml-1的头孢呋辛钠浓度范围内 ,浓度与旋光度值呈良好的线性关系。回归方程 :C =1 4 .74 90α +0 .1 74 2 (r=0 .9999)。平均回收率1 0 0 .4 % ,RSD =1 .36 %。结论 所用方法操作简便、快捷准确 。
OBJECTIVE To establish a method for the determination of Sodium cefuroxime injection. METHODS Polarimetry was used with water as solvent.RESULTS The linear relationship between the concentration and the optical rotation was good in the concentration range of 2-10 mg.ml -1 .The regression equation was C =14.7490α+0.1742, and the correlation coefficient was 0.9999.The average recovery was 100.4% and RSD was 1.36%.CONCLUSION The method was accurate and easy to perform.It is suitable for quantity control and rapid analysis in the preparation.
出处
《华西药学杂志》
CAS
CSCD
2003年第3期219-220,共2页
West China Journal of Pharmaceutical Sciences
