摘要
目的 :探讨老年人脑卒中后癫痫的临床特点和发病机制。方法 :对 6 3例脑卒中后继发癫痫的老年患者临床资料进行回顾性分析。结果 :老年人脑卒中后癫痫的发生率为 5 .89% ,与病灶部位 (皮质 /皮质下 )密切相关 ,两者比较有显著性差异(P<0 .0 1)。本组患者中迟发型癫痫 4 7例 (74 .6 0 % ) ,部分性发作 4 0例 (6 3.4 9% )。结论 :老年人脑卒中后癫痫以迟发型和部分性发作为主 ,皮质病灶易发生癫痫。脑水肿、神经元细胞膜稳定性破坏而致痫性放电是早发型癫痫的主要机制 。
Objective:To explore the clinical features and mechanisms in elderly patients with postapoplectic epilepsy Methods:Clinical manifestations were retrospectively investigated in 63 elderly patients with postapoplectic epilepsy Results:The incidence of postapoplectic epilepsy in the elderly patients was 5 89%,which was closely related to the locations of seizure focus(cortex/subcortex).The difference between them was magnificant(P<0 01).47 patients showed late onset epileptic seizure(74 60%) and 40 patients showed partial epilepsy (63 49%) Conclusions:Postapoplectic epilepsy in elderly patients mainly shows late onset seizure and partial epilepsy.Cortex focus are more likely to cause epileptic attack.The cerebral edema and neuron membrane damaged are the main factors of early onset epileptic seizure,while the hyperplasia of the neuroglia around the apoplectic focus may cause the late epilepsy
出处
《广西医学》
CAS
2003年第6期918-920,共3页
Guangxi Medical Journal