摘要
目的 观察银杏达莫治疗糖尿病周围神经病 (DPND)的疗效。方法 将 56例DPND患者随机分成 2组 ,各 2 8例 ,对照组采用DPND的常规治疗方法 ,治疗组在对照组用药基础上加用银杏达莫 ,每日静滴 2 0ml,治疗并在治疗 1 6周后观察患者症状和体征、肝肾功能、血糖以及神经传导速度变化情况。结果 治疗 1 6周后 ,银杏达莫治疗组对改善DPND患者的肢体疼痛、麻木、发凉、感觉异常和 或减退等临床症状的总有效率为 75 .0 % ,较对照组 53 .6 %有非常显著性差异 (P <0 .0 1 ) ;对神经传导速度的改善率 53 .6 % ,较对照组 2 1 .4%有非常显著性差异 (P <0 .0 1 ) ,而银杏达莫对肝肾功能、血糖等无影响。结论 银杏达莫对改善DPND患者的临床症状有明显疗效 ,且可以改善神经传导速度 。
Objective To evaluate the therapeutic effect of Ginkgo Dipyidamolum on the patients with diabetic peripheral nerve diseases (DPND).Methods 56 patients with DPND were randomly divided into two groups.28 patients in group A (control group) were treated by routine therapy;28 patients in group B (treatment group),on the treatment basis of group A,were treated with Ginkgo Dipyidamolum by intravenous infusions,20ml daily for 16 weeks.The symptoms and physical signs of patients,the functions of liver and kidney,blood sugar and nerve conduction velocity (NCV) were observed.Results The total effective rate in improving the clinical symptoms was 75.0% in group B and 53.6% in group A.There was a significant difference between two groups (P<0.01).The improvement rate for NCV was 53.6% in group B,compared with 21.4% in group A,the difference between two groups was significant (P<0.01).The effect of Ginkgo Dipyidamolum on the functions of liver and kidney was not observed in all patients.Conclusion Ginkgo Dipyidamolum is effective in improving the clinical symptoms and NCV of DPND patients.
出处
《疑难病杂志》
CAS
2003年第2期79-81,共3页
Chinese Journal of Difficult and Complicated Cases
关键词
糖尿病周围神经病
银杏达莫
治疗
疗效
临床分析
Diabetic peripheral nerve diseases
Ginkgo Dipyidamolum
Nerve conduction velocity
