摘要
含铁细胞或称为铁传递色素(Siderochores)是微生物合成的低分子量化合物,并与细胞内铁传递有关,正铁色素是其中的一种,而人工合成的模拟化合物具备了正铁色素的主要功能基团和相近的化学性质。本工作利用铁(Ⅲ)离子的顺磁性质,用核磁共振方法测定不同铁(Ⅲ)离子浓度下模拟正铁色素分子上质子的诱导弛豫时间,根据简化了的S-B公式。计算出铁(Ⅲ)离子到所有被测质子的相对距离,并结合分子模型,比较清楚地得到模拟正铁色素在溶液中的构象。
The ferrichrome analogues are of the main function of natural ferrichrome. In this work, the relaxation times of the ferrichrome analogue 1368C at different Fe(Ⅲ) concerntrations have been measured, and the relative distances from Fe(Ⅲ) ion to most of protons have been also worked out by using a simplified Solomon-Bloembergen equation. The conformation of this complex in CDCl_3 solution can be imagined out.
