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21d-6°头低位卧床对肺气体分布和小气道功能影响的实验观察

Effects of 21d-6°Head Down Bed rest on Pulmonary Gas Distribution and Little Airway Function.
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摘要 :目的探讨 2 1d - 6°头低位卧床 (HDBR)对气体分布和小气道功能的影响。方法采用Vmax2 2LV肺功能仪 ,对 1 6名健康男性被试者卧床前、后及卧床不同时间反映小气道功能的指标 (ΔN2 、CV、CV/VC %、LCI)进行了测试。结果ΔN2 在恢复期平卧位与卧床前平卧位及卧床早期比较其增加有统计学意义 ;CV仅在卧床第 1天 (HDBR 2 0min左右 )测量值与卧床前平卧位比有显著增加 ,CV/VC %的变化与之一致 ;LCI的变化不明显。结论 2 1d - 6°头低位卧床对气体分布有影响。CV仅在头低位卧床开始阶段一过性的增加 ,2 1d - 6°头低位卧床使气体分布不均有增加趋势。 Objective To probe the effect of 21 d -6°head down bed rest (HDBR) on pulmonary gas distribution and little airway function. Method The indices of the pulmonary gas distribution and little airway function(ΔN 2,CV,CV/VC%,LCI)were measured in 16 healthy male subjects before, during and after 21 d -6°HDBR. Result Comparing with before and early days of HDBR, recovery supine ΔN 2 increased significantly. CV increased significantly only on the first day of HDBR, and changes of CV/VC% were same as CV. The changes of LCI were not significant. Conclusion The indices of pulmonary gas distribution were affected by 21 d -6° HDBR. Pulmonary gas distribution was more uneven during and after 21 d -6°HDBR.
出处 《航天医学与医学工程》 CAS CSCD 北大核心 2003年第2期93-95,共3页 Space Medicine & Medical Engineering
关键词 模拟失重 头低位卧床 气体分布 小气道功能 weightlessness simulation head down bed rest gas distribution little airway function
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