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骨髓基质干细胞与成骨的研究进展 被引量：4

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摘要 实验证实骨髓基质干细胞具有间充质干细胞的特性 ,表现为较强的增殖能力和向多种间充质细胞分化的潜能 ,可向成骨系细胞方向分化。在体外培养时具成骨细胞样细胞表型 ,植入体内可产生矿化骨组织。
作者 许燕凯 杨应明
机构地区 汕头大学医学院第一附属医院神经外科
出处 《汕头大学医学院学报》 2003年第1期57-59,共3页 Journal of Shantou University Medical College
基金 广东省教育厅自然科学研究项目 (A2 0 0 0 44 3 )
关键词 骨髓基质干细胞 成骨 研究进展 细胞培养 成骨分化
分类号 R329－33 [医药卫生—人体解剖和组织胚胎学]
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参考文献19

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  • 5Otsuka E, Yamaguchi A, Shigehisa H et al. Characterizations of osteoblastic differentiation of stromal cell line ST2 that is induced by ascorbic acid. Am J Physiol, 1999, 277 (Cell Physiol 46) : C132 - C138.
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同被引文献48

  • 1杨福军,夏玉莲,李雨民,孙元明,刘征,刘宗礼,李贺达,杨学琪.自体成骨细胞的诱导培养及其生物学特性[J].中国骨质疏松杂志,2004,10(3):263-266. 被引量：3
  • 2庞全海,张慧茹,华进联,马勇江,窦忠英.山羊骨髓间充质干细胞生物学性能鉴定及诱导分化为心肌细胞的研究[J].中国农学通报,2005,21(5):1-4. 被引量：5
  • 3杨兴华,刘运生.骨髓基质干细胞的研究现状及其展望[J].泰山医学院学报,2005,26(6):604-606. 被引量：2
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  • 5Beresford JN. Osteogenic stem cells and the stromal system of bone and marrow. Cliu Orthop Relat Res 1989; (240): 270- 80
  • 6Schantz.JT, Teoh SH, Lim TC, et al. Repair of calvarial defects with customized tissue-engineered bone grafts I. Evaluation of osteogenesis in a three-dimensional culture system. Tissue Eng 2003; 9 Suppl 1:S113 -26
  • 7Hillmann G, Gebert A, Geurtsen W. Matrix expression and proliferation of primary gingival fibroblasts in a three-dimensional cell culture model. J Cell Sci 1999; 112 ( Pt 17): 2823-32
  • 8Kim SS, Sundback CA, Kaihara S, et al. Dynamic seeding and in vitro culture of hepatocytes in a flow perfusion system. Tissue Eng 2000; 6(1): 39 -44
  • 9Beck LS, Wong RL, DeGuzman L, et al. Combination of bone marrow and TGF-beta1 augment the healing of critical-sized bone defects. J Pharm Sci 1998;87(11): 1379 -86
  • 10Noshi T, Yoshikawa T, Dohi Y, et al. Recombinant human bone morphogenetic protein-2 potentiates the in vivo osteogenic ability of marrow/hydroxyapatite composites. Artif Organs 2001; 25 (3): 201-8

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汕头大学医学院学报
2003年 第1期

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