摘要
目的 考察金裕星注射液稳定性 ,并预测其室温贮存有效期。方法 紫外分光光度法测定金裕星注射液含量 ,用初匀速法预测其有效期。结果 金裕星注射液在 5～ 1 0 μg·mL- 1 范围内呈良好线形关系 (r =0 .9999) ,平均回收率 1 0 0 .0 7% ,RSD0 .1 2 %。结论 初匀速法预测金裕星注射液有效期简便、迅速。金裕星注射液稳定性好 ,室温 2 5℃贮存期 4 .1 9年。
OBJECTIVE To survey the stability of Jinyu Star injection at 25℃ and predict its expiry term. METHOD Jinyu Star injection was determined by UV spectrophotometry, its expiry date was predicted by an initial average rate method.RESULTS The linear range of Jinyu Star injection was 5～10μg·mL -1 (r=0.9999).The average recovery of Jinyu Star injection was 100.07%, RSD 1.2%.CONCLUSION Initial average rate method is convenient and rapid. Stability of Jinyu Star injection is good, expiry of term predicted at 25℃ is 4.19 years. Initial average rate method provides a scientific basis for clinical application.
出处
《中国现代应用药学》
CAS
CSCD
北大核心
2003年第2期163-164,共2页
Chinese Journal of Modern Applied Pharmacy
