摘要
目的 :探讨胞必佳胸腔注射对肺癌恶性胸腔积液的治疗作用。方法 :确诊肺癌恶生胸腔积液患者 72例 ,胞必佳 4 0 0～ 6 0 0ug加生理盐水 4 0ml于排去胸液后胸腔内注入 ,观察胸液变化和疗效。结果 :总有效率达 94 .4 % ,多数患者注射 1～ 3次 ,注射后胸水白细胞总数明显升高 ,分类由以淋巴细胞为主转化为以中性白细胞为主 ,r-干扰素也明显升高 ,多数患者胸水癌细胞转为阴性 ,部分患者有发热。结论 :胞必佳胸腔注射治疗肺癌恶性胞腔积液效果佳 ,副作用小。
Objective: To study results of N-CWS (nocardia rubra cell wall skeleton) treatment through intrapleural instillation in malignant pleural effusion of lung cancer. Methods: Seventy-two cases of malignant pleural effusion in lung cancer were treated by intrapleural instillation N-CWS 400～600ug. Result: The effective rate were 94.4%, most of cases received instillation one to three time. After instillation, white blood cells count increases obviously, and the predominant cells change from lymphocytes to mononuclear cells and polymorphonuclear leukocytes in the pleural fluid. Interferon-gamma(IFN-r) increases obviously too in the pleural fluid. Conclusion: Intrapleural treatment of N-CWS is effective for malignant pleural effusion in pulmonary carcinoma. It's a good choice in clinic.
出处
《河北医学》
CAS
2003年第3期220-222,共3页
Hebei Medicine
关键词
胞必佳
胸腔注射
治疗
肺癌
恶性胸腔积液
临床研究
Nocardia cell well skeletor(N-CWS)
Lung cancer
Malignant pleural effusion
Treatment
