摘要
目的 :研究冠心病 (CHD)患者甘油三酯水平与血浆凝血因子Ⅶc (FⅦc)、组织型纤溶酶原激活剂(tPA)及其抑制物 (PAI I)活性的相关性。方法 :73例确诊CHD患者分为两组 :高甘油三酯组 (2 4例 ) ,正常甘油三酯组 (49例 )。 80例对照者亦分为高甘油三酯组 (40例 )和正常甘油三酯组 (40例 )。血清甘油三酯浓度测定采用酶法 ;PAI I及tPA测定采用发色底物法 ;FⅦc测定采用一期法。结果 :CHD患者及对照者中高甘油三酯者FⅦc、PAI I活性均有升高 ,tPA活性下降 ,其中高甘油三酯CHD患者改变最为显著 (P <0 .0 1)。结论 :高甘油三酯与FⅦc、tPA、PAI Ⅰ有明显相关性 。
Objective:To investigate the correlation among serum triglyceride concentration, plasma factorⅦ clouting(FⅦc), tPA, PAI I activity in 73 cases with Coronary heart disease(CHD).Methods:153 Cases Were divided into four groups:73 patients with CHD were divided into two groups based on serum triglyceride concertration. 40 subjects have high triglyceride without CHD; another 40 subjects with normal triglyceride. The results in 73 patients with CHD and 40 Subjects With High triglyceride were compared with that in 40 normal triglyceride. Serum triglyceride was measured by enzyme method, The plasma PAI0 I, tPA activity by spectorphotometry, the plasma FⅦc by onestage method.Results:FⅦc and PAI I activity in patients with CHD and in serum high triglyceride group were higher than in those with normal triglyceride group. FⅦc and PAI I activity in high triglyceride patients with CHD were significantly higher than in those high triglyceride cases without CHD.Conclusion:Serum high triglyceride concentuition is associatied with FⅦc, tPA and PAI 1.
出处
《临床心血管病杂志》
CAS
CSCD
北大核心
2003年第4期205-206,共2页
Journal of Clinical Cardiology
