摘要
以 3 2只小鼠为材料 ,采用对照的方法 ,对正常对照组和游泳组小鼠心电活动的变化进行了比较分析。主要分析指标为Ⅱ导联宽频带心电图时域值及QRS波群和Q—T间期的功率谱。经过 15 0～ 160min的游泳后 ,小鼠宽频带心电图的各项时域值及功率谱较正常组发生了不同程度的变化 :心率变慢 ,由正常组的 5 66± 12 4次 /min减慢为游泳组的 44 0± 114次 /min ;P—R间期由 3 3 .7± 2 .7ms延长为 3 9.3± 3 .1ms;P波时程由 8.0± 0 .8ms延长为 8.9± 0 .9ms;P—R段由 2 5 .7± 2 .5ms延长为 3 0 .4± 3 .1ms。以上变化均有显著性差异 (P <0 .0 5或P <0 .0 1)。而QRS波群时程由 8.8± 0 .9ms延长为 9.1± 0 .8ms;Q—T间期由 18.7± 1.7ms延长为 18.9± 1.4ms;T波时程由 9.9± 1.7ms缩短为 9.7± 1.1ms。QRS波群峰—峰值由1.42 5± 0 .3 2 7mv增大为 1.5 18± 0 .3 15mv ;T波高度由 0 .5 45± 0 .0 99mv增大为 0 .5 90± 0 .143mv ,这些变化均无显著性差异。在QRS波群和Q—T间期的功率谱中 ,游泳组高频相对能量有所增加 。
We divided thirty-two mice into control group and swimming group, then analyzed the variation of ventricular electrical activity in normal mice and swimming mice. The chief analysis index was time domain (Lead Ⅱ) and power spectrum (including QRS complex and Q-T interval) of wide frequency band electrocardiogram (WFB-ECG) in mice. The time domain and power spectrum of WFB-ECG in swimming mice (swimming time, 150～160 minutes) changed in different degrees compared with normal mice. The results were as follows: the heart rate changed from 566±124 beats/min in control group to 440±114 beats/min in swimming group; P-R interval prolonged from 33.7±2.7ms to 39.3±3.1ms; duration of P prolonged from 8.0±0.8ms to 8.9±0.9ms; P-R segment prolonged from 25.7±2.5ms to 30.4±3.1ms. These changes were significant (P<0.05 or P<0.01). Duration of QRS complex widened from 8.8±0.9ms to 8.9±0.9ms; Q-T interval prolonged from 18.7±1.7ms to 18.9±1.4ms; duration of T decreased from 9.9±1.7ms to 9.7±1.1ms. Vp-p of QRS complex increased from 1.425±0.327mv to 1.518±0.315mv; amplitude of T increased from 0.545±0.099mv to 0.590±0.143mv. The high frequency relative power of QRS complex and Q-T interval increased a bit in swimming mice,these changes were not significant.
出处
《山东生物医学工程》
2003年第1期24-27,共4页
Shandong Journal of Biomedical Engineering
基金
山东省自然科学基金项目 (Y2 0 0 2D18)
