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脂质体肺部给药的研究 被引量:2

Recent Researches on Pulmonary Drug Delivery of Liposomes
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摘要 由于脂质体肺部给药具有刺激性小、吸收迅速、生物利用度高、安全性好、可实现持续缓慢释药等独特优势而成为近年来制剂领域的研究热点之一。本文论述脂质体肺部给药的特点、稳定性以及在药代动力学、药效学和安全性等方面的最新研究进展。 Pulmonary drug delivery of liposomes has become one of research foc i in the area of pharmaceutics owing to its specific advantages, such as low irr itation, rapid ab sorption, high bioavailability, satisfactory safety, sustained or controlled rel ease, and so on. Recent researches on pulmonary delivery of liposomes in propert ies, stability, pharmacokinetics, pharmacodynamics and safety are reviewed.
作者 陈军 方芸
出处 《药学进展》 CAS 2003年第2期85-88,共4页 Progress in Pharmaceutical Sciences
关键词 脂质体 给药途径 肺部给药 特点 稳定性 药物代谢动力学 药效学 Liposome Pulmonary drug delivery Pharmacodynamics Pharmacokinetics Safety
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