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胰岛素抵抗与脂肪肝 被引量:30

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摘要 目前越来越多的研究提示胰岛素抵抗是代谢综合征的病理生理基础,而胰岛素抵抗又与血循环、肝细胞内的游离脂肪酸的蓄积、脂肪细胞中肿瘤坏死因子-α超表达以及铁的蓄积、瘦素等因素息息相关,从而影响脂肪肝和非酒精性脂肪性肝炎的发病,因此胰岛素抵抗可能并不是脂肪肝的继发改变,而可能是其原发始动因素。
作者 顾鸣宇
出处 《国外医学(内分泌学分册)》 2003年第B04期32-33,共2页 Foreign Medical Sciences(Section of Endocrinology)
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