摘要
目的:研究肝癌患者血浆IL-1活性及TNF-α含量,为进一步探索肝癌发病机理提供资料。方法:应用同位素掺入法、酶联法检测了肝癌患者血浆白细胞介素-1(IL-1)活性和肿瘤坏死因子α(TNF-α)含量。结果:肝癌患者血浆IL-1活性明显低于对照组,而血浆TNF-α含量却显著高于对照组。结论:肝癌患者巨噬细胞活性受抑制,TNF可能部分来自肝癌细胞的自身分泌。
objective: To study the activities of IL- 1 and content of TNF-α in plasma from patients of Hepatocarcinoma take e-valuated IL - 1 and TNF-α play a role in pathogenesis of hepatocarcinoma. Method: Using bioassay tecnique were studied. Results: The activties of IL- 1 from patients of hepatocarcinoma were decreased remarkably in compared controls. The contents of TNF -α from patients of hepatocarcinoma increased significantly. Conclusion: IL - 1 and TNF - α has played a role in pathogenesis of hepatocarcinoma and may as useful laboratory parameter for the inducement patients of hepatocarcinoma condition.
出处
《中国厂矿医学》
2003年第1期4-5,共2页
Chinese Medicine of Factory and Mine
基金
吉林省卫生厅课题953557-2
