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肝素、纳洛酮及氨溴索联合应用治疗肺性脑病的临床研究 被引量:1

Clinical study of pulmonary encephalopathy treated with combination of heparin,naloxoen and ambroxol HCL
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摘要 目的 研究肝素、纳洛酮及氨溴索联合应用治疗肺性脑病的疗效。方法 将 90例肺性脑病病人随机分为三组。A组 30例采用常规方法治疗 ;B组 30例常规方法 +肝素 ;C组 30例常规方法 +肝素 +纳洛酮 +氨溴索。三组疗程均为 1周 ,并观察其疗效及血气分析变化。结果 A、B、C三组总有效率分别为6 0 %、83 3%、96 7% ,B组、C组与A组疗效比较差异有显著意义 (P <0 0 5 ,P <0 0 1)。结论 加用肝素、纳洛酮及氨溴索联合治疗肺性脑病疗效显著 ,可迅速改善临床症状 ,使用安全 ,不良反应少 ,值得临床推广应用。 Objective To study the efficacy of heparin,naloxoen and ambroxol combined with usual methods in the treatment of pulmonary encephalopathy.Methods Ninety cases of pulmonary encephalopathy were randomly divided into 3 groups.Thirty cases in group A were treated with usual methods;Thirty cases in group B were treated with heparin in addition to the usual methods;Thirty cases in group C were treated with heparin,naloxoen and ambroxol added to usual method.Treatment period lasted for one week.Efficacy was evaluated and the changes of blood gas analysis were observed.Results Total effective rates were 60%,83.3% and 96.7% in group A,B,and C respectively.The differences between group A and B and between A and C were significant(P<0.05,P<0.01).Conclusion Adding heparin,naloxoen and ambroxol to the usual treatment of pulmonary encephalopathy has great efficacy.It can improve clinical signs promptly and is safe in use.
出处 《中国基层医药》 CAS 2003年第2期122-123,共2页 Chinese Journal of Primary Medicine and Pharmacy
关键词 肝素 纳洛酮 氨溴索 联合治疗 应用 肺性脑病 Heparin Naloxoen Ambroxol HCL Pulmonary disease Pulmonary encephalopathy
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  • 1徐淑云.临床药理学(下)[M].上海:上海科技出版社,1998.71.

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