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抗心磷脂抗体与急性心肌梗死相关性研究 被引量:25

Study on the correlation of anticardiolipin antibody and acute myocardial infarction
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摘要 目的 了解抗心磷脂抗体 (ACA)与急性心肌梗死 (AMI)的相关性。方法 用ELISA法对5 6例健康人和 10 6例缺血性心脏病患者的ACA水平进行检测。结果 ACA阳性百分率对照组为 1 8% ,冠心病组为 4 2 0 % ,急性心梗组为 83 9% ;2 1例ACA阳性的冠心病患者有 6例分别于 6~ 2 4个月发生AMI,ACA阴性的 2 9例患者无AMI发生 ;5 6例AMI患者中 ,年龄在 30~ 4 2岁的 8例患者ACA全部为阳性。结论 部分缺血性心脏病的发病可能与ACA阳性有关 ,尤以AMI相关性明显 ,对冠心病是否会发生急性心肌梗死 。 Objective To observe the correlation of anticardiolipin antibody(AGA) and acute myocardial infarction Methods ELISA was used to determine the ACA levels in 56 healthy people and 106 patients with ischemic heart diseases.Results The positive rate of ACA was 1 8% in control group,42 0% in coronary heart disease group and 83 9% in acute myocardial infarction group.The acute myocardial infarction occurred in 6 of 21 patients with coronary heart diseases with positive ACA within 6 to 24 months,but the acute myocardial infarction didnt occur in the patients of coronary heart diseases with negative ACA.Out of the 56 cases of patients with acute myocardial infarction,8 cases aged between 30 and 42 had positive ACA.Conclusion Positive ACA probably correlates with the morbidity of ischemic heart diseases,especially in acute myocardial infarction.ACA can also predict the morbidity of acute myocardial infarction in those with coronary heart disease. [
出处 《中华急诊医学杂志》 CAS CSCD 2003年第2期114-115,共2页 Chinese Journal of Emergency Medicine
关键词 急性心肌梗死 抗心磷脂抗体 相关性 发病学 ELISA法 Anticardiolipin antibody Ischemic heart disease Coronary heart disease Myocardial infarction
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