1Auwerx J, Staels B. Leptin. Lancet, 1998,351 : 737-742.
2Ahima RS, Flier JS. Leptin. Annu Rev Physiol, 2000, 62.413-437.
3Sharrna K, Considine RV, Michael B. Plasma leptin is partly cleared by the kidney and is elevated in hemodialysis patients. Kidney Int, 1997, 51:1980-1985.
4Widjaja A, Kielstein JT, Horn R, et al.Free serum leptin but not bound leptin concentrations are elevated in patients with end-stage renal disease. Nephrol Dial Transplant, 2000, 15 ;846-850.
5Nordfors L, Lonnqvist F, Heimburger O, et al. Low leptin gene expression and hyperleptinemia in chronic renal failure. Kidney Int, 1998,54:1267-1275.
6Praga M, Hernandez E, Herrero JC, et al.Influence of obesity on the appearance of proteinuria and renal insufficiency after unilateral nephrectomy. Kidney Int, 2000,58:2111-2118.
7Heimburger O, Lonnqvist F, Danielsson A,et al. Serum immunoreactive lepfin concentration and its relation to the body fat content in chronic renal failure. J Am Soc Nephrol, 1997, 8:1423-1430.
8Stenvinkel P, Heimburger O, Lonnqvist F.Serum leptin concentrations correlate to plasma insulin concentratins independent of body fat content in chronic renal failure.Nephrol Dial Transplant, 1997, 12: 1321-1325.
9Wolf G, Hamann A, Han DC, et al. Leptin stimulates proliferation and TGF-βexpression in renal glomerular endothelial cells: potential role in glomerulosclerosis. Kidney Int,1999, 56:860-872.
10Han DC, Isono M, Chen S, et al. Leptin stimulates type Ⅰcollagen production in db/db mesangial cells: glucose uptake and GF-βtype Ⅱ receptor expression. Kidney Int, 2001,59:1315-1323.
