摘要
目的:观察肝酶灵注射液对大鼠慢性肝损伤的保护作用。方法:采用颈后皮下注射CCl_4致大鼠慢性肝损伤为模型,测定肝酶灵注射液对肝损伤大鼠AST5、ALT、ALP和白蛋白/球蛋白的影响,同时对肝组织进行病理组织学检查。结果:肝酶灵注射液能降低慢性肝损伤大鼠血清AST、ALT、ALP含量,升高白蛋白/球蛋白,减轻肝组织的病理变化,保护肝组织的超微结构。结论:肝酶灵注射液对大鼠慢性肝损伤有显著的保护作用。
Objective:To study protective effect of Injection Ganmeiling on chronic hepatic injury. Methods: The activity of AST, ALT and ALP in serum and histopathological change were determined in hepatic injury rats induced by CCL;. Results: Ganmeiling obviously inhibited the rising of AST, ALT and ALP in serum.The histopathological examination showed that Ganmeiling could alleviate the condition of necrosis and the degenration of hepatic cells. Conclusion: The results suggested that Ganmeiling could protect liver from hepatic injury induced by CCl4.
出处
《中药材》
CAS
CSCD
北大核心
2003年第2期111-112,共2页
Journal of Chinese Medicinal Materials
基金
广州市重点技术攻关项目
编号为(JB02)97-Z46-067
