摘要
在碱性缩合剂存在下,由N-酰基噻唑啶-2-硫酮分别同丙二酸二乙酯及乙酰乙酸乙酯进行缩合,生成α-酰基丙二酸二乙酯(2_(a～d)),产率为67～78％;酰基乙酰乙酸乙酯(3_a,3_o),产率为60～65％。
On the basis of using 3-acylthiazolidine-2-thione as the acylating agent, a new method for the synthesis of c-aeylated malonie and acetoacetic esfers (2_(a～d), 3_a, 3_e) is reported in this paper. These acylations were performed preferably in THF at room temperature for 24 h with NaH used as the condensing agent. The yield of 2_(a～d) is 67～78％, 3_a 65％ and 3_e 60％.
出处
《吉林大学自然科学学报》
CSCD
1989年第4期107-109,共3页
Acta Scientiarum Naturalium Universitatis Jilinensis
关键词
酰基
噻唑啶硫酮
丙二酸二乙酯
α-acylethylmalonate, α-acylethytacetoacetate.
